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The weekend sees the inaugural Wear-Tyne derby after 2024, but who will emerge victorious – the Black Cats or the Magpies?
"For most of last season, no one would have predicted Sunderland earning promotion and challenging with Eddie Howe's Newcastle, let alone being above them in the table," commented analyst Chris Sutton.
"Things are very different now, and the way they play convinces me they've got a genuine opportunity."
Sutton is making forecasts for all 380 Premier League games this campaign, against artificial intelligence, readers and a range of guests.
For this weekend's fixtures, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the England's esports team – the Football Association's recognised esports team – at the gaming title digital Euros finals tournament, which will occur at Twickenham Stadium on Saturday.
The action will be streamed on Uefa's video platform, Instagram Live and short-form video channels, as well as the official Twitch channel and its YouTube counterpart and England's Twitch.
Are you in alignment with their forecasts? Share your own projections below.
The fan-favourite scoreline picked for each game is featured in the tables at the foot of this page.
Predicting the right outcome (choosing a win, draw or defeat) is worth 10 points. A perfect prediction earns 40 points.
Ray, who also plays Gen City and the Premier League champions as well as England, is making his debut at the eEuros finals after passing the qualifying.
A group of eight will represent their nations at the finals in a straight knockout, playing for a six-figure prize fund and a highly sought-after spot in the global championship qualifiers, with the Danish representative Anders Vejrgang defending the title he won last year.
"I am feeling really good for it," Ray stated. "I have a really good coach with me and practice has been going well.
"It is invariably an honour to play for your country. Obviously when you are younger, you fantasise about doing it as an professional footballer, but when you enter this profession and there is an chance to represent England, putting the shirt on is something incredible.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd always lost to him in a tournament before.
"For me he is the best player in the world so beating him in a tournament like this just delivers a huge surge of confidence."
Premier League Predictions
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were excellent against Arsenal at the end of November, when they got a draw after being reduced to 10 men, and many thought here we go, they could potentially be challengers for the crown.
In the matches following, however, they were beaten physically by Leeds, looked lethargic against Bournemouth and this week got defeated by Atalanta in the Champions League.
So manager Enzo Maresca desperately requires a win here to return to winning ways, but it won't be easy because Everton are such a dangerous team.
Two of their stars are playing really well and they have got a bit of a positive run at the moment.
Current evidence suggests you would likely back the visitors, while the most sensible prediction would likely be a draw, but I am not going to be sensible.
Chelsea haven't given me any compelling evidence to back them recently, but I just have a feeling they will win this match because they are at home and they are in need of three points.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be intriguing to see what we get from Liverpool.
I am really pleased for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot ought not to put up with that drama. I know Salah has been a great for the club but fundamentally Slot just wants to win games and there is no bias in his team selection.
They changed their shape against Inter and went with a midfield diamond formation and two up top.
All the talk is going to be talking about whether Salah is selected for this game, but the only way he is going to be brought back into the fold is if he apologises.
Slot's focus will be on winning this game, but it is a difficult fixture.
You could argue it is the same for most teams but I find Brighton so hard to predict. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to stringing wins together, but I am not sure how much their energy spent at the San Siro will have affected their stamina.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will likely do poorly - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
Sunderland have had the benefit of a free week while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
With the exception of their excellent performance against Everton a couple of weeks ago, Newcastle's away form hasn't been great, especially straight after they've played in the Champions League.
The pattern suggests that trend to continue on Sunday, and their tiredness is likely to be a key element in how this game goes because of their rivals' energetic style.
We saw how incessant Regis le Bris's side are. They bullied the Gunners, and it was a joy to watch.
Everyone talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays next to him, has also been one of the best acquisitions and should be recognised too.
All signs point to this being the best game|most exciting fixture